I can only emphasise that "something like this" is not the target group of the case. The fans can be replaced, but I cannot judge whether there is enough space for a water cooling system.

If in doubt, it is better to choose a card with fan cooling and take the overall length into account.

TB3 also results in power losses, which is why this combination would also not be ideal.

But otherwise, you will unfortunately have to try it out for yourself.

As the performance is somewhat reduced by the Chroma, I don't recommend it anyway. The case also does not support water cooling.